Researchers from the Royal Institute of Technology in Sweden have developed a substance that will create biocompatible “patches” on the site of damaged bone tissue. And thus eliminate them without installing metal pins or plates. As a basis, they took the polymer resin, which is already used for tooth filling.
The principle of the patch for bones is identical to how they work with teeth. First, an acidic ointment is applied to the damaged area, to etch the surface and expose the collagen fibers. Then they put a layer of polymer resin, which contains microparticles – they adhere to the fibers of collagen and create a stable connection. It remains to light the patch to trigger the thiol-alkene reaction of curing the substance.
Swedish scientists have developed a special version of the polymer resin, which in addition to strength provides the necessary level of flexibility of bone substance. It is 55% more effective than a simple resin, if you believe the results of experiments on the bones of rats. Now the technology is being prepared for clinical trials, and if they are successful, Biomedical Bonding AB will create a commercial version of the drug.
The technique has colossal prospects associated with the fact that earlier the very idea of bonding bones remained the lot of fiction. There was no suitable material for this. Now, in theory, it will be possible to cure an arbitrarily complex fracture – it will be approximately the same as gluing a broken vase. Difficult, risky, but possible.js.src = “&version=v2.8”; 'script', 'facebook-jssdk'));